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Delta-9 vs Delta-10: Comparing the Effects and Benefits of Each

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Picking your ideal cannabinoid from the cannabis smorgasbord can feel a bit like trying to find the perfect wave for surfers—it's all about timing, understanding, and a little bit of adventurous spirit.

This guide aims to clarify your decision-making process, focusing on two notable cannabinoids: delta-9 and delta-10 THC.

Key Takeaways: Delta 9 vs. Delta 10 THC

  • Delta-9 and delta-10 THC interact with the body's endocannabinoid system, but their effects can be distinct.
  • Delta-9 THC, more prevalent and potent, is renowned for its strong psychoactive effects.
  • Delta-10 THC is less potent and known to provide an uplifting, energizing experience.
  • Delta-9 has been studied extensively, with evidence supporting its use in pain and arthritis management.
  • Delta-10, while promising, requires more research to understand its full potential.
  • Most adults can safely consume both cannabinoids, but long-term effects need further exploration for delta-10.
  • Shopping for products from reputable, third-party tested sources ensures safety and quality.

What is Delta-9 THC?

delta-9 THC molecule structure

Delta-9 THC, or delta-9-tetrahydrocannabinol, is the most renowned cannabinoid (cannabis-derived chemical compound). Known for producing the primary psychoactive effects associated with cannabis, delta-9 interacts with the body's endocannabinoid system (ECS) to induce euphoria, relaxation, and altered sensory perception.

In other words, it's the molecule responsible for the high that people typically associate with marijuana use.

Structurally, it consists of 21 carbon atoms, 30 hydrogen atoms, and 2 oxygen atoms. This compound's uniqueness lies in its chain's double bond on the 9th carbon atom, hence its name, delta-9.

What is Delta-10 THC?

Delta-10 THC molecule structure

A relative newcomer to the cannabinoid scene, delta-10 THC is a close chemical sibling to delta-9.

More specifically, delta-10 THC is an isomer of delta-9 THC, which means it has the same chemical formula but a different arrangement of atoms. The difference lies in the placement of the double bond in the molecule. In delta-10 THC, the double bond is on the 10th carbon chain.

Naturally found in only trace amounts within the hemp plant, it's prized for its unique effects that some users describe as more stimulating and focus-enhancing than other forms of THC.

While both delta-9 and delta-10 THC have psychoactive properties, their effects can vary considerably.

Users often report that delta-10 THC produces a more uplifting and stimulating effect, leading to heightened focus, creativity, and energy.

On the other hand, delta-9 THC is known for creating a more intense psychoactive experience, which is the classic "high" that people often associate with cannabis use.

It's important to note that these effects can vary depending on many factors, including individual biology, the method of consumption, the dosage, and more. Therefore, while delta-10 THC is generally reported to have milder effects than delta-9 THC, some people may still experience intense effects or side effects.

Differences Between Delta-9 and Delta-10:

  • Chemical Structure: Although they share a similar molecular framework, the location of their double bonds distinguishes delta-9 from delta-10.
  • Effects: Delta-9 is known for inducing strong psychoactive effects, while Delta-10 may promote an uplifting and energizing experience.
  • Potency: Delta-9 THC is typically more potent and pronounced in its effects than Delta-10.
  • Availability: Delta-9 THC is abundant in cannabis plants, while delta-10 is present only in minuscule amounts.

Similarities Between Delta-9 and Delta-10:

  • Both delta-9 and delta-10 are cannabinoids originating from the cannabis plant.
  • Each possesses psychoactive properties, though the intensity and nature of their effects can differ.
  • They both interact with the endocannabinoid system within the body.
  • The 2018 Farm Bill federally legalizes both, granted they are derived from hemp and the finished product contains less than 0.3% delta-9 THC by dried weight basis.

Comparison tablet of delta 9 vs delta 10 specs

Delta-9 vs Delta-10 for Pain

When it comes to cannabinoids and pain management, delta-9 THC has been the subject of much more research and clinical studies compared to its counterpart, delta-10 THC, since it's a minor cannabinoid with much less scientific backing.

Delta-9 THC for Pain

Delta-9 THC has been studied extensively for its potential therapeutic applications, particularly in the area of pain management. It's been found to have analgesic properties, meaning it can relieve pain. Some of these studies include:

  1. A meta-analysis published in 2015 looked at 28 studies (2,454 participants) on the use of cannabinoids for chronic pain, nausea, and appetite stimulation. The analysis concluded that there is substantial evidence that cannabis (most studies used extracts that contain delta-9 THC) is an effective treatment for chronic pain in adults [1].
  2. In a study published in the European Journal of Internal Medicine, researchers reported that elderly patients who used cannabis (containing delta-9 THC) for pain management experienced significant pain reduction and improved quality of life [2].
  3. Nabiximols, a THC: CBD oromucosal spray, showed mixed results in chronic cancer-related pain trials. However, it demonstrated more consistent analgesic efficacy in chronic neuropathic pain, particularly related to MS, with some patients benefiting for up to 2 years [3].

These studies and others like them suggest that delta-9 THC could be an effective tool for managing different types of pain, including chronic pain, neuropathic pain, and pain associated with cancer and other serious illnesses.

Medical marijuana programs already exist as a result of findings like this. However, despite these promising results, limitations such as short study durations, heterogeneous patient populations, and decades of bad PR for the compound mean that it may take more work yet to delta-9 THC in the mainstream for its health benefits.

Delta-10 THC for Pain

As for delta-10 THC, much less is known about its potential benefits for pain relief. This is largely because it's a relatively new compound in the market, and it's found in such tiny amounts in the cannabis plant that it's been difficult to study.

While some anecdotal reports suggest that delta-10 might have pain-relieving properties, clinical research has not yet backed these claims. Some users of delta-10 products have reported a distracting or uplifting effect that can help to distract from pain or discomfort temporarily, but this is highly individual and not grounded in scientific evidence.

As such, if you're considering using cannabinoids for pain management, delta-9 THC currently has more supporting evidence.

However, the world of cannabinoid research is rapidly evolving, and we might see more studies on delta-10's potential benefits in the future.

Delta-9 vs. Delta-10 for Arthritis

Delta-9 THC has been the focus of several studies exploring its potential therapeutic effects on arthritis symptoms because of its potential analgesic and anti-inflammatory effects.

A study published in the European Journal of Pain found that many patients with arthritis reported pain relief after using a cannabis-based medicine, Sativex, which contains delta-9 THC and cannabidiol (CBD) [4].

In particular, this study found improved sleep quality in these patients, reducing one of the common debilitating symptoms of arthritis.

Another study in Arthritis Research & Therapy showed that the use of a cannabis-based medicine reduced disease activity in patients with rheumatoid arthritis, suggesting a potential role for delta-9 THC in arthritis management [5].

Again, compared to delta-9, there's less research on delta-10 THC in relation to arthritis. 

Current information about delta-10 THC largely comes from anecdotal evidence, suggesting that its uplifting and energizing effects may help distract from pain or discomfort associated with arthritis. However, these reports are highly subjective and can vary widely among users.

Where to Buy Delta-9 and Delta-10 Products

When looking for delta-9 and delta-10 THC products, the most crucial factors are the legality in your region, the brand's reputation, and the product's safety and efficacy.

Neurogan Hemp-Derived THC Products

Neurogan Delta 9 THC Gummies compared to Neurogan Delta 10 THC gummies

One reputable source for hemp-derived THC products is Neurogan. We offer a range of high-quality, hemp-derived THC products that are federally legal under the 2018 Farm Bill.

This includes products that contain delta-9 THC derived from hemp and maintain a delta-9 THC concentration of less than 0.3%. Our products are made using sustainable farming practices and are third-party lab-tested for safety and purity.

However, just because these products are federally legal doesn't mean they're legal in all states. Some states have laws restricting the purchase and use of hemp-derived THC products. Therefore, it's essential to familiarize yourself with the laws in your state before placing an order.

Online and Local Stores

Aside from Neurogan, various online and local stores also carry delta-9 and delta-10 THC products. These might include dispensaries in states where recreational marijuana use is legal.

Online marketplaces also offer a vast array of THC products. Just be aware that you should always check the laws in your state before purchasing, as some states have restrictions on shipping THC products.

Lab Results and Safety

Finally, remember that not all THC products are created equal.

Always prioritize your safety by checking lab results before making a purchase. Any reputable brand should have its products tested by a third-party lab, and the results should be easily accessible to consumers.

These lab reports will verify the cannabinoid content in the product and ensure it's free of harmful contaminants like heavy metals, pesticides, and residual solvents.

Delta-9 and Delta-10 THC Safety Concerns

When it comes to discussing the safety of cannabinoids such as delta-9 and delta-10 THC, the conversation needs to be nuanced. Several individual factors, including a person's health, tolerance levels, consumption quantity, and administration method, can significantly influence their safety profile.

Delta-9 THC Safety

Delta-9 THC, the most potent form of THC in cannabis, is known for its strong psychoactive effects.

Although short-term use is generally safe, long-term or heavy use can lead to cognitive impairments, mental health issues, and potential dependency. It can also interact with other medications and cause anxiety or disorientation in large doses.

Delta-10 THC Safety

Delta-10 THC is less potent than delta-9 and relatively new on the market, thus less researched.

Its use might result in an uplifting experience. However, due to its novelty, comprehensive research on its long-term effects is lacking. If you're curious about delta-10 THC, you should purchase from reputable sources offering third-party lab test results.

The Takeaway: Delta-9 vs. Delta-10

Choosing between delta-9 and delta-10 THC comes down to your personal adventure.

If you're up for a robust, well-studied trip, delta-9 is your companion. But if you're in for a gentle, exciting journey, hitch a ride with the lesser-known delta-10.

While delta-9 has had more time under the research spotlight, don't count out delta-10 just yet.

Remember, as you explore these new terrains, shop smart — look for quality, third-party-tested products, and when in doubt over these compounds' potential medicinal benefits, ask your healthcare professional, as they can provide you with personalized advice.


Is Delta 10 stronger than Delta 9?

Delta 10 is generally considered to be milder than Delta 9 in its psychoactive effects. While both are cannabinoids found in the cannabis plant, Delta 9 is typically associated with stronger psychoactive experiences.

Should I get Delta 9 or 10?

Delta 9 offers strong psychoactive effects, while Delta 10 provides a less intense high. The choice between the two cannabinoids depends on your desired effects.

What is the difference between Delta 9 vs Delta 10 gummies?

Delta 9 gummies offer a potent, traditional psychoactive effect, while Delta 10 gummies has a mild, uplifting experience. Individual responses may vary based on dosage and individual tolerance.

What is the strongest THC variant?

Delta-9 THC is the strongest and most potent THC variant, known for its intense psychoactive effects. If you are seeking a milder experience with fewer side effects, consider Delta 10.


  1. Whiting, P. F., Wolff, R. F., Deshpande, S., Di Nisio, M., Duffy, S., Hernandez, A. V., ... & Kleijnen, J. (2015). Cannabinoids for medical use: a systematic review and meta-analysis. Jama313(24), 2456-2473.
  2. MacCallum, C. A., & Russo, E. B. (2018). Practical considerations in medical cannabis administration and dosing. European journal of internal medicine49, 12-19.
  3. Überall, M. A. (2020). A review of scientific evidence for THC: CBD oromucosal spray (nabiximols) in the management of chronic pain. Journal of pain research, 399-410.
  4. Blake, D. R., Robson, P., Ho, M., Jubb, R. W., & McCabe, C. S. (2006). Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology45(1), 50-52.
  5. Richardson, D., Pearson, R. G., Kurian, N., Latif, M. L., Garle, M. J., Barrett, D. A., ... & Chapman, V. (2008). Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. Arthritis research & therapy10, 1-14.
Nicklas Brandrup

BSc International Business, Copenhagen Business School Nicklas is the co-founder of Neurogan and a serial entrepreneur with a proven track record in the health and wellness space.  Nicklas has generated more than $250M in sales on Amazon with brands that he owns and operates. He is passionate ab...

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